Thanks to the recent advances in reproductive medicine, more and more young women with breast cancer may be offered the possibility of preserving their fertility. Fertility can be endangered by chemotherapy, by treatment duration and by patient’s age at diagnosis. The currently available means to preserve a young woman’s fertility are pharmacological protection with gonadotrophin-releasing hormone analogues during chemotherapy, and ovarian tissue or oocyte/embryo freezing before treatment. New future venues, including in vitro maturation, will improve the feasibility and efficacy of the fertility preservation methods in breast cancer patients.
Fedro A. Peccatori, Lino del Pup, Francesca Salvagno, Maurizio Guido, Maria A. Sarno, Alberto Revelli, Luisa delle Piane, Elisabetta Dolfin, Dorella Franchi, Emanuela Molinari, Valentina Immediata, Leonora Chiavari, Alessandra Vucetich, Andrea Borini; Breast Care, 2012;7:197-202.