A new approach to evaluate aging effects on human oocytes: Fourier transform infrared imaging spectroscopy study
Abstract OBJECTIVE: To characterize from a vibrational point of view the alterations caused by aging on human oocytes. DESIGN: Reproductive biology. SETTING: Private assisted reproductive technology clinic, synchrotron beam line, and university infrared laboratory. PATIENT(S): Twenty women of different ages (30 ± 2 and 39 ± 2 years) selected on the basis of detailed inclusion criteria and submitted to controlled